Health Advice

Tracleer is a relatively new drug which is commonly used to treat Primary Pulmonary Hypertension (PPH). This condition increased blood pressure in the lungs and puts excessive strain on the heart, reducing its ability to function effectively.

It works by reducing blood levels of a molecule called endothelin, which is naturally present in the blood. The amount of endothelin in the blood is increased to a dangerous level in people with Primary Pulmonary Hypertension. It is thought that these increased levels of endothelin are actually one of the causes of PPH, because endothelin causes blood vessels to constrict, and therefore elevates blood pressure.

Primary Pulmonary Hypertension is a serious disease, and currently it is not curable. However, the progress of the disease can be slowed and the severity of symptoms can be alleviated with the use of drugs such as Tracleer. All of the drugs used in PPH treatment do have side effects, some of which are unpleasant or serious and require careful monitoring. However, Primary Pulmonary Hypertension has very severe consequences if left untreated, and the benefits of medication outweigh the risks of side effects.

Please note that this article should not be used as a substitute for professional medical help. If you experience any symptoms that are not noted here, consult your doctor or another medical professional as soon as possible.

Side Effects of Tracleer

Minor side effects include flushed skin, headaches, irritation of the nose or throat, and stomach upsets. These side effects are common for people undergoing this treatment. The severity of these symptoms may decrease as your medication dosage is adjusted, and it can take time before an optimal dose is established.

Any occurrence of side effects should be reported to your doctor while your treatment program is being established and at any other time if they become persistent. While these side effects are not necessarily serious or life-threatening, they may indicate that your Tracleer treatment dosage requires adjustment, or that you may be responding to PPH treatment in an abnormal fashion.

The following side effects are more serious and require immediate medical attention.

* Coughing up blood
* Dizziness or fainting
* Irregular heartbeat or a pounding feeling in the chest
* Lightheadedness
* Shortness of breath
* Swelling of the legs or ankles
* Sudden weight gain

Allergic Reactions

If you are allergic to it, your symptoms may include:

* A rash or hives on the skin
* Itching of the skin
* Shortness of breath
* A feeling of tightness in the chest
* Swelling of the tongue or throat
* Swelling of the lips or other facial features

Seek medical attention immediately if any of these side effects occur, as a severe allergic reaction can be fatal if untreated.

Liver Damage – Signs to watch for

The use of it can cause a reduction in liver function, and may cause serious liver damage. Before and during it’s treatment, you will be required to undergo liver function tests to monitor your liver for side effects.

While taking it, look for the following warning signs that may indicate liver problems: nausea or vomiting, fever or stomach pain, yellow skin or yellow eyes, dark urine, pale-colored bowel movements, or excessive tiredness. If any of these symptoms occur, consult with your doctor. You will most likely need to undergo liver function tests, and your doctor may decide to adjust your treatment plan or discuss alternative treatments to prevent further liver damage.

Note that at this time it is thought that the liver damage caused by this treatment is not permanent. In most cases of liver damage caused by it, normal liver function returns after the treatment is stopped.

Drug Interactions

Tracleer interacts with a wide variety of prescription and over-the-counter medicines which can reduce the effectiveness of it or cause other side effects. If you are taking any other medications prior to or while taking Tracleer it is vital to make sure your doctor is aware of these. Because commonly-used medications such as Advil and Aleve can reduce the effectiveness of it, it is also important to seek medical advice before using any over-the-counter drugs while taking Tracleer for PPH treatment.

Tracleer is also known to reduce the effectiveness of most oral and injected birth control medications as well as implanted contraceptive devices. Because it also causes severe birth defects if taken during pregnancy, it is very important that women taking it use additional or alternative forms of birth control to avoid becoming pregnant.

Nick Johnson is lead counsel with Johnson Law Group. Johnson represents plaintiffs in many states and focuses on injury cases involving Fen-Phen and PPH, Paxil, Mesothelioma and Nursing Home Abuse. Call Nick Johnson at 1-888-311-5522 or visit http://www.jbclawfirm.com

Many people diagnosed with Primary Pulmonary Hypertension (PPH) experience similar feelings: they feel scared, overwhelmed by the disease and its implications, and even confused about how it could have happened. If your disease is the result of Fen-Phen use, you may also be feeling angry. Whatever you’re feeling, understand that it is normal. You will likely run the gamut of emotions by the time your doctor has established an effective PPH treatment and you have returned to a more normal lifestyle.

No matter how you feel, Primary Pulmonary Hypertension and PPH treatment are much easier to cope with if you stay involved in the treatment process, and gain as much knowledge about the disease and your treatment as possible.

It is difficult to maintain a sense of security at a time when many aspects of your life may feel out of control. Getting as much information as possible about the disease and your treatment options can help a great deal with these feelings. Most patients as well as doctors agree that having this information can make it easier to cope with the disease and with treatment.

After being diagnosed, the process of establishing a treatment plan is often long and exhaustive. People tend to have unique responses to PPH treatment medications, and the only sure way to know which medication will work most effectively is to try each in turn until the most effective treatment is found. Depending on your responses to each drug, your doctor may decide that Tracleer treatment is your best option, and this drug has its own unique set of risks which may be difficult to cope with.

It is important that you feel as comfortable as possible during diagnosis and treatment processes. Ask as many questions of your doctor as you feel are necessary. There are no “wrong” questions. Included here is a list of possible questions to ask your doctor. You may find it helpful to write these down, and include any other questions that come to you.

Remember that information not only helps you feel more in control, it will make you safer as well. If you and your friends and family know as much as possible about the disease, its symptoms, the side effects of PPH treatment and the side effects of this treatment, it will enable you to get help more quickly if you experience any of them.

* How severe is your condition? What is your long-term prognosis?
* What symptoms might you experience in the future?
* Which of these are “warning-signs”? What should you do if you experience these?
* What are your treatment options? Is this treatment the best choice?
* What are the side effects of it?
* What tests will your doctor do to determine if the treatment is working?
* What kinds of lifestyle changes should you make?
* Are there any activities, foods, or over-the-counter medications you should avoid?

There are two serious side effects associated with Tracleer treatment that may leave you feeling even more overwhelmed or scared if your doctor decides this is the best PPH treatment for you.

It is known to cause liver damage, and it is also not prescribed for pregnant women because of the damage it causes to unborn babies. For this reason, it is not possible to become pregnant while taking it. For young women who are hoping to start a family, this can be devastating thing to have to accept.

For people with Primary Pulmonary Hypertension who are undergoing this treatment and PPH treatment in general, another way to help reduce the anxiety and get some needed emotion support is by finding a support group in your area. Your doctor or another health professional may be able to recommend a group near you.

If you are unable to find a support group using this method, the Pulmonary Hypertension Association web site provides a list of support groups available in all US regions, as well as in other countries of the world. Getting in touch with other people who share your concerns and who are going through the same things you are can help make PPH less frightening and easier to cope with.

Although PPH is not curable, the PPH treatments available make it possible to achieve a much more normal lifestyle than was possible even ten years ago. Staying positive with this disease can be difficult, but with knowledge of the disease, and the support of family and friends it is possible.

Nick Johnson is lead counsel with Johnson Law Group. Johnson represents plaintiffs in many states and focuses on injury cases involving Fen-Phen and PPH, Paxil, Mesothelioma and Nursing Home Abuse. Call Nick Johnson at 1-888-311-5522 or visit http://www.jbclawfirm.com

Pulmonary hypertension refers to a medical condition in which there is an elevated blood pressure in the pulmonary artery which can restrict blood flow to the lungs and cause the heart’s right ventricle to overwork itself, leading to a variety of symptoms (including dizziness, fainting, and shortness of breath) as well a marked decreased ability to exert oneself (such as through exercise or a lot of activity).

The term primary pulmonary hypertension (PPH), although it’s now being used less in the medical realm in favor of the term idiopathic pulmonary arterial hypertension, is still a term used readily in literature as well as in the general public, and refers to pulmonary hypertension that has an unknown or unverified cause.

PPH has many possible causes, but because the term primary pulmonary hypertension was coined due to the fact that its cause is unknown, specific causes are difficult to pinpoint. Causes of the different types of pulmonary hypertension in general can include left heart failure, congenital heart disease, lung diseases, HIV and other autoimmune disorders, pulmonary embolism, and genetics.

One of the biggest suspected causes of primary pulmonary hypertension is the use of certain anti-obesity and weight-loss pills, such as Fen-Phen, which the FDA took off the market in September 1997 after reports linked it to pulmonary hypertension and other conditions.

If you have primary pulmonary hypertension, you’ll want to consider an effective PPH treatment. One of the most popular and beneficial PPH treatments is an FDA-approved drug called Tracleer. Why is this treatment so beneficial? Tracleer treatment, produced by Patheon Inc. and marketed by Actelion Pharmaceuticals, is a vasodilator drug in tablet form that is taken orally in order to help block the effects of endothelin, a vasoconstrictor naturally found in the body to shrink blood vessels, but is found in much higher concentrations in patients with primary pulmonary hypertension.

In addition, PPH treatment using this helps to relax the lung’s blood vessels as well as increase the level of oxygen in the blood. For patients with primary pulmonary hypertension, what this means in a practical sense is that they are able to perform regular activities at an improved level, without becoming fatigued, dizzy, or short of breath right away, and they are able to tolerate exercise more.

However, like all drugs, including others used for PPH treatment, it does have a number of side-effects that patients taking it or considering its use should become aware of. Some of the more common side-effects associated with this treatment include headaches, nasal congestion, flushing out, passing out, and even abnormally low blood pressure.

The most serious possible side-effect associated with this treatment, however, involves the liver. Tracleer can actually impair normal liver function, and even cause liver damage, which may or may not be permanent in nature. As a result, patients with primary pulmonary hypertension on this treatment require monthly blood tests of the liver’s function.

In addition to side-effects, Tracleer treatment also has one major contraindication: pregnant women or women who may be or are trying to become pregnant must not take it, as this particularly form of PPH treatment has been proven to be teratogenic (known to harm a fetus, cause birth defects, or miscarriage).

Therefore, in addition to monthly liver blood tests, female patients on it must take monthly pregnancy tests in case pregnancy occurs, at which point it must be stopped immediately. Further, if you’re a female on Tracleer treatment and you’re using a hormonal method of birth control, you will also have to supplement with a barrier method (like condoms) because it has been shown to reduce the effectiveness of birth control pills, patches, rings, injections, and implants.

While this treatment often has more side-effects and potential complications than other types of PPH treatment, such as Flolan and Remodulin (two of the other most common types of PPH treatment), it is the preferred type for many because of its convenience in that it can be taken orally.

Patients with primary pulmonary hypertension may wish to talk to their doctors about different types of PPH treatment, including Tracleer treatment. It is available by prescription only and should only be taken under a doctor’s advice and directions.

If you have pulmonary hypertension with an unknown cause, and you believe you may have developed primary pulmonary hypertension because of your use of the anti-obesity, weight-loss pill Fen-Phen, then in addition to asking your doctor about Tracleer treatment, it is recommended you seek the legal counsel from a reputable law firm or PPH attorney specializing in Fen-Phen litigation cases. You may qualify for compensation.

Nick Johnson is lead counsel with Johnson Law Group. Johnson represents plaintiffs in many states and focuses on injury cases involving Fen-Phen and PPH, Paxil, Mesothelioma and Nursing Home Abuse. Call Nick Johnson at 1-888-311-5522 or visit http://www.jbclawfirm.com

Primary Pulmonary Hypertension is a serious condition, and the drugs that are used to treat it (such as Flolan and Tracleer) are effective, but do have some potentially serious side effects and symptoms to watch out for. Some of these side effects may be unpleasant to live with, however leaving Primary Pulmonary Hypertension untreated has much more severe consequences.

Minor Side Effects of Flolan

Minor side effects include the following symptoms. These side effects are fairly common in patients being treated with Flolan (note that some of these symptoms are caused by Flolan being administered intravenously rather than by the drug itself).

Some of these side effects are commonly experienced by individuals who are beginning treatment, and the symptoms may subside as the medication dosage is adjusted to optimal levels. If you experience any of these side effects, see your doctor for advice; especially if they become persistent or particularly irritating or painful.

* Abnormal sensations on the skin (such as a “crawling” feeling) or an altered ability to feel sensations
* Anxiety, agitation, or nervousness
* Pain, swelling or redness at the site of injection
* Back pain
* Stomach pain, stomach upset, or diarrhea
* Headache, dizziness, or nausea
* Pain in the jaw or muscles
* Sweating
* Vomiting

Serious Side Effects of Flolan

The following side effects are considered more serious, these include a possible allergic reaction to the drug as well as side effects caused by the drug itself. If you experience any of these side effects, it’s important to seek medical attention immediately. Do not substitute reading this article for medical advice, and please consult your doctor for a more complete list of side effects.

Symptoms of severe allergic reaction include a rash or hives on the skin, itching of the skin, shortness of breath, a feeling of tightness in the chest, and swelling of the tongue or facial features. Any of these symptoms indicate that a dangerous allergic reaction is occurring, and immediate medical attention should be sought.

Other serious side effects of Flolan include:

* Chest pain
* Irregular or fast heartbeat
* Headache, muscle pain or bone pain
* Swelling in the abdominal area
* Unusual or unexplained bruising, or a tendency to bruise easily
* Bleeding gums or nosebleeds
* A feeling of general weakness

In addition, you should also watch out for any signs of infection at the injection site. These may include symptoms such as pain, swelling, redness or bleeding. Any signs of infection, including sudden fever, should be reported to your doctor as soon as possible.

As you can see, some of these side effects can be considered both minor and serious, depending on the circumstances. For this reason, it is important to seek medical advice whenever any of these symptoms are experienced. Only your doctor will know for sure if these symptoms are a cause for alarm.

Not all of these side effects are serious in themselves (a bleeding nose is not in itself life-threatening) but some of these side effects may indicate that your Flolan treatment dosage needs to be adjusted, or that your body may be responding to your PPH treatment in an unexpected way.

If you have any unexplained symptoms that are not on these lists, consult your doctor as soon as possible. Any unexplained effects should be monitored to make sure they are not serious or life-threatening.

Drug Interactions

Flolan is known to interact with a wide variety of prescription medications as well as some over-the-counter medicines, and the list of such medications is much too long to include here. If you are taking any other medications (including prescription and over-the counter medications and supplements) in addition to Flolan it is vital to make sure your doctor is aware of these.

Even commonly-used medications such as Tylenol and many forms of Aspirin can reduce the effectiveness of Flolan, so it is also important to seek medical advice before taking any other medications while you are using Flolan for PPH treatment.

Nick Johnson is lead counsel with Johnson Law Group. Johnson represents plaintiffs in many states and focuses on injury cases involving Fen-Phen and PPH, Paxil, Mesothelioma and Nursing Home Abuse. Call Nick Johnson at 1-888-311-5522 or visit http://www.jbclawfirm.com

There are many conditions that can cause one to encounter stress in one’s life. Here are some of the many conditions that lead an individual to suffer from stress.

Health problems: Often if you suffer from heart problems , diabetes, or arthritis you may encounter chronic stress.

Emotional problems: There are many emotions that one may encounter on daily basis that can lead one into suffering from stress. If you often fine oneself , angry; depressed; grief stricken; feeling guilty; or encounter low self-esteem, you could be suffering from chronic stress.

Relationship problems: Often in relationships one may encounter stress due to a fight between partners; lack of having someone to share your feelings with; or feeling isolated from the rest of the world.

Your surrounding: Often in big cities , the number of individuals suffering from stress rises due to crime; pollution; overcrowding; and from the noise of people and automobiles.

Your job: One’s job can truly stress an individual out. If your job is very demanding; requires you to meet production; dangerous; or requires one to publicly speak in crowds, you stand a greater chance of developing a stress condition.

Your social situation: Social life is always going to cause certain individual’s stress. If one has to deal with poverty; loneliness; or discrimination due to one’s gender; race; or sexual orientation, it will cause one to suffer from chronic stress.

Life cycles and developmental stages: As a child , you may encounter stress. If one is picked on or mistreated they may become isolated due to the stress of the situation they have to encounter. As children grow up and become teenagers, they experience stress due to their hormones changing ; dating; working a job; associating with different people; and leaving home.

When one becomes an adult they suffer even more depression in one’s life. They have to worry about working; supporting oneself; family; partners; and getting or being married.

Many times , people set goals for oneself and often find they can achieve their goal. This is often a very stressful situation for one to endure. You should set your perceptions of what you want to achieve at a moderate level. Stick to your beliefs about oneself. Don’t let anyone lower your self-esteem. You have but one to live.

There are many children; teens; and other family members that are constantly under stress because of one’s physical or emotional condition. One may find it very beneficial to talk to a friend and let one’s inner feelings be known. It is better to let your voice be heard than to keep things held up inside oneself.

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